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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCC
All Species:
45.76
Human Site:
T209
Identified Species:
77.44
UniProt:
Q15814
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15814
NP_003183.1
346
39220
T209
H
Q
R
D
V
L
L
T
E
L
S
N
C
T
V
Chimpanzee
Pan troglodytes
XP_518477
346
39236
T209
H
Q
R
D
V
L
L
T
E
L
S
N
C
T
V
Rhesus Macaque
Macaca mulatta
XP_001088723
346
39322
T209
H
Q
R
D
V
L
L
T
E
L
S
N
C
T
V
Dog
Lupus familis
XP_538923
388
42549
T251
H
Q
R
D
V
L
L
T
E
L
S
K
C
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCN9
341
38106
S204
H
Q
R
D
V
L
L
S
D
L
T
N
C
T
V
Rat
Rattus norvegicus
NP_001101670
340
38058
S203
H
Q
R
D
I
L
L
S
D
L
T
N
C
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508991
335
37102
S198
L
Q
R
D
I
L
L
S
G
L
T
D
C
T
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922489
350
39443
S204
Q
Q
R
D
V
L
L
S
H
L
T
H
C
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722959
355
40503
S194
N
G
Q
D
I
T
I
S
K
L
N
H
C
L
V
Honey Bee
Apis mellifera
XP_001120828
342
39209
S205
N
K
N
D
I
L
L
S
D
L
I
R
C
T
I
Nematode Worm
Caenorhab. elegans
Q27249
256
29613
E128
D
E
A
K
V
I
A
E
D
A
D
R
K
Y
E
Sea Urchin
Strong. purpuratus
XP_783718
353
39965
S216
Y
L
K
D
V
S
L
S
N
L
S
S
C
T
V
Poplar Tree
Populus trichocarpa
XP_002307082
324
36492
S187
E
I
G
E
F
T
L
S
D
L
D
S
C
E
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_195702
345
38291
S204
S
I
G
E
F
T
L
S
D
L
D
S
C
Q
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.3
72.9
N.A.
76
74.5
N.A.
61.5
N.A.
N.A.
43.7
N.A.
33.5
38.7
21.1
39.6
Protein Similarity:
100
99.1
97.6
78.3
N.A.
84.3
83.5
N.A.
74.5
N.A.
N.A.
64
N.A.
57.7
58
40.1
62.6
P-Site Identity:
100
100
100
93.3
N.A.
80
73.3
N.A.
60
N.A.
N.A.
60
N.A.
26.6
40
6.6
53.3
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
86.6
N.A.
N.A.
80
N.A.
80
80
26.6
80
Percent
Protein Identity:
29.7
N.A.
N.A.
32.3
N.A.
N.A.
Protein Similarity:
48.2
N.A.
N.A.
51.7
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
8
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
93
0
0
% C
% Asp:
8
0
0
79
0
0
0
0
43
0
22
8
0
0
0
% D
% Glu:
8
8
0
15
0
0
0
8
29
0
0
0
0
8
8
% E
% Phe:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
15
0
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
43
0
0
0
0
0
0
0
8
0
0
15
0
0
0
% H
% Ile:
0
15
0
0
29
8
8
0
0
0
8
0
0
0
8
% I
% Lys:
0
8
8
8
0
0
0
0
8
0
0
8
8
8
0
% K
% Leu:
8
8
0
0
0
65
86
0
0
93
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
8
0
0
0
0
0
8
0
8
36
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
58
8
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
58
0
0
0
0
0
0
0
0
15
0
0
0
% R
% Ser:
8
0
0
0
0
8
0
65
0
0
36
22
0
0
0
% S
% Thr:
0
0
0
0
0
22
0
29
0
0
29
0
0
65
0
% T
% Val:
0
0
0
0
58
0
0
0
0
0
0
0
0
0
86
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _